In an effort to facilitate collaborations and speed GWI research, the GWIRP has compiled a list of various research resources produced from our funding. The list displays available resources and contact information. Please contact the PI(s) directly for information and requests.

Award Number PI Product(s) References Contact Information


Ronald Bach

CRP-Associated Plasma Biomarkers of Inflammation

Johnson GJ, Leis LA, Slater BCS, et al. 2013. Elevated platelet count, CRP and thromboxane analog-induced platelet aggregation in subjects with Gulf War Veterans' Illnesses: Evidence of a chronic inflammatory state? Blood Coagul Fibrinolysis 24(7):736-741.

Johnson GJ, Slater BCS, Leis LA et al. 2016. Blood Biomarkers of Chronic Inflammation in Gulf War Illness. PLoS ONE 11(6): e0157855.doi:10.1371/journal.pone.0157855


James Baraniuk

Cardiovascular indices and imaging based biomarkers post exercise challenge

Rayhan RU, Stevens BW, Raksit MP,et al. 2013. Exercise challenge in Gulf War Illness reveals two subgroups with altered brain structure and function. PLoS One 8(6):e63903


James Baraniuk

Exercise – induced changes in cerebrospinal fluid miRNAs

James N. Baraniuk, Narayan Shivapurkar. 2017. Exercise-induced changes in cerebrospinal fluid miRNAs in Gulf War Illness, Chronic Fatigue Syndrome and sedentary control subjects. Scientific Reports 7: 15338 DOI:10.1038/s41598-017-15383-9. PMID: 29127316


Nancy Klimas, Gordon Broderick

Altered immune pathway activity

Broderick G, Ben-Hamo R, Vashishtha S, et al. 2013. Altered immune pathway activity under exercise challenge in Gulf War Illness: An exploratory analysis. Brain, Behavior, and Immunity 28 (2013) 159 — 169


Jarred Younger

Immune factors to predict daily symptom severity in GWI

Parkitny L, Middleton S, Baker K, et al. 2015. Evidence for abnormal cytokine expression in Gulf War Illness:

A preliminary analysis of daily immune monitoring data. BMC immunology 16(1):57.


Lisa Pierce

miRNA and epigenetic biomarkers

Pierce LM, Kurata WE, Matsumoto KW, Clark ME, and Farmer DM. 2016. Long-term epigenetic alterations in a rat model of Gulf War Illness. Neurotoxicology 55:20-32.


Beatrice Golomb

Alterations in mitochondrial function (prolonged PCr-recovery time constant)

Koslik HJ, Hamilton G, and Golomb BA. 2014. Mitochondrial dysfunction in Gulf War illness revealed by 31Phosphorus Magnetic Resonance Spectroscopy: a case-control study. PLoS One 9(3):e92887.


Apostolos Georgopoulos

inflammatory markers, C-reactive protein associated with symptom severity; erythrocyte sedimentation rate; autoimmune markers;

James LM, Engdahl BE, Johnson RA, Georgopoulos AP. Gulf War Illness and Inflammation: Association of symptom severity with C-reactive protein. J Neurol Neuromed. 2019; 4(2): 15-19.



Ghania Ait-Ghezala Laila Abdullah

lysophospholipid species (lysophophatidylcholine and lysophosphatidylethanolamine); IL-1beta, IL-6, IFNgamma, CCR2, CCL2

Emmerich T, Zakirova Z, Klimas N, Sullivan K, Shetty AK, Evans JE, et al. (2017). Phospholipid profiling of plasma from GW veterans and rodent models to identify potential biomarkers of Gulf War Illness. PLoS ONE 12(4): e0176634.


Kimberly Sullivan, Mohamed Abou Donia

serum autoantibodies

Abou-Donia MB, Lapadula ES, Krengel MH, Quinn E, LeClair J, Massaro J, Conboy LA, Kokkotou E, Abreu M, Klimas NG, Nguyen DD, Sullivan K. Using Plasma Autoantibodies of Central Nervous System Proteins to Distinguish Veterans with Gulf War Illness from Healthy and Symptomatic Controls. Brain Sci. 2020 Sep 5;10(9):610. doi: 10.3390/brainsci10090610. PMID: 32899468; PMCID: PMC7563126.


Marco Loggia

TSPO marker of cerebral neuroinflammation using PET imaging

Alshelh Z, Albrecht DS, Loggia ML, et al. In-vivo imaging of neuroinflammation in veterans with Gulf War illness. Brain Behav Immun. 2020 Feb 4. pii: S0889-1591(19)31334-0. PMID: 32027960



Beatrice Golomb

increases in ceramides, sphingomyelins and phosphatidylcholine lipids in plasma of ill Gulf War veterans

Robert K. Naviaux, Beatrice A. Golomb, et al. Metabolic features of Gulf War illness. 2019. PLoS One.2019 Jul 26;14(7) PMID: 31348786


Ashok Shetty

biomarkers of neuroinflammation (HMGB-1, TNFa, IL6) and complement activation (C3 and TccC5b-9) in the brain in an animal model

Madu LN, Attaluri S, Shetty AK, et al. Neuroinflammation in Gulf War Illness is linked with HMGB1 and complement activation, which can be discerned from brain-derived extracellular vesicles in the blood. Brain, Behavior, and Immunity 81 (2019) 430–443. PMID: 31255677


Kaundinya Gopinath

functional network connectivity

Gopinath KS, Sakoglu U, Crosson BA, et al. Exploring brain mechanisms underlying Gulf War Illness with group ICA based analysis of fMRI resting state networks. Neuroscience letters. 2019 May; 701: 136-141. PMID:30825590



Bang-Bon Koo / Kimberly Sullivan

neurite density imaging (NDI) + machine learning of structural changes in the brain

Guan Y, Cheng C-H, Chen W, Zhang Y, Koo S, Krengel M, Janulewicz P, Toomey R, Yang E, Bhadelia R, Steele L, Kim J-H, Sullivan K, Koo B-B. Neuroimaging Markers for Studying Gulf-War Illness: Single-Subject Level Analytical Method Based on Machine Learning. Brain Sciences. 2020; 10(11):884. PMID: 33233672

Last updated Thursday, May 26, 2022