DEPARTMENT OF DEFENSE - CONGRESSIONALLY DIRECTED MEDICAL RESEARCH PROGRAMS
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NEWS RELEASE

Released: January 31, 2014

Department of Defense Neurofibromatosis Research Program
Funding Opportunities for Fiscal Year 2014 (FY14)

The FY14 Defense Appropriations Act provides $15 million (M) to the Department of Defense Neurofibromatosis Research Program (NFRP) to support innovative, high-impact neurofibromatosis research. This program is administered by the US Army Medical Research and Materiel Command (USAMRMC) through the Office of Congressionally Directed Medical Research Programs (CDMRP).

The NFRP is providing the information in this pre-announcement to allow investigators time to plan and develop applications. FY14 NFRP Program Announcements and General Application Instructions for the following award mechanisms are anticipated to be posted on the Grants.gov website in March 2014. Letter of intent and application deadlines will be available when the Program Announcements are released. This pre-announcement should not be construed as an obligation by the government. Funding is contingent on receipt of appropriations.

Areas of Emphasis: The NFRP encourages applications that specifically address the critical needs of the NF community in one or more of the FY14 Areas of Emphasis. Not all Areas of Emphasis are applicable to each award mechanism offered by the FY14 NFRP. If the proposed research project does not address one of the FY14 Areas of Emphasis, justification that the proposed research project addresses an important problem related to NF research and/or patient care should be provided.

  • Health services for NF
  • Heterogeneity of neurofibromas and other NF-related tumors
  • Manifestations of NF post-adolescence
  • Mechanisms of pain
  • Novel disease markers for NF using genomics, epigenetics, system biology, metabolomics, or other similar approaches
  • Target identification and drug discovery for the treatment of NF

Award Mechanism PI Eligibility Funding
Clinical Trial Award Must be an independent investigator at or above the level of Assistant Professor (or equivalent)
  • Maximum funding of $900,000 in direct costs (plus indirect costs)
  • Period of performance should not exceed 4 years
Exploration - Hypothesis Development Award All levels of experience
  • Maximum funding of $100,000 in direct costs (plus indirect costs)
  • Period of performance should not exceed 2 years
Investigator-Initiated Research Award Must be an independent investigator at or above the level of Assistant Professor (or equivalent)
  • Maximum funding of $525,000 in direct costs (plus indirect costs)
  • Maximum funding of $575,000 in direct costs (plus indirect costs) for applications including an Optional Qualified Collaborator
  • Period of performance should not exceed 3 years
New Investigator Award Must be an independent investigator at or below the level of Assistant Professor (or equivalent) or an established investigator at or above the level of Assistant Professor seeking to transition into a career in NF research
  • Maximum funding of $400,000 in direct costs (plus indirect costs)
  • Period of performance should not exceed 3 years

All applications must conform to the final Program Announcements and General Application Instructions that will be available for electronic downloading from the Grants.gov website. The application package containing the required forms for each award mechanism will also be found on Grants.gov. A listing of all USAMRMC funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.

Applications must be submitted through the federal government's single-entry portal, Grants.gov. Submission deadlines are not available until the Program Announcements are released. Requests for email notification of the Program Announcements release may be sent to help@cdmrp.org. Email notifications of funding opportunities are sent as a courtesy and should not be used as a sole source of notification; applicants should monitor Grants.gov for official postings of funding opportunities.

For more information about the NFRP or other CDMRP-administered programs, please visit the CDMRP website (https://cdmrp.army.mil).

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