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Reconstructive Transplant Research

NEWS RELEASE

Released: May 31, 2018

Defense Health Program
Department of Defense Reconstructive Transplant Research Program
Funding Opportunities for Fiscal Year 2018 (FY18)

The FY18 Defense Appropriation provides $12 million (M) to the Department of Defense Reconstructive Transplant Research Program (RTRP) to support research projects that specifically address needs in the field of vascularized composite allotransplantation (VCA). The managing agent for the anticipated Program Announcements/Funding Opportunities is the Congressionally Directed Medical Research Programs (CDMRP) at the U.S. Army Medical Research and Materiel Command (USAMRMC).

The RTRP is providing the information in this pre-announcement to allow investigators time to plan and develop applications. FY18 RTRP Program Announcements and General Application Instructions for the following award mechanisms are anticipated to be posted on the Grants.gov website in June 2018. Pre-application and application deadlines will be available when the Program Announcements are released. This pre-announcement should not be construed as an obligation by the Government.

Focus Areas: The FY18 RTRP encourages research projects that specifically address needs in the field of vascularized composite allotransplantation (VCA) in the following focus areas:

  • Reduce the risks of VCA-associated immunotherapy
  • Revolutionize ex vivo VCA tissue preservation strategies to extend the timeline between procurement and transplantation
  • Identify near- and long-term functional, quality-of-life, and psychosocial outcomes in VCA
Award Mechanism Eligibility Key Mechanism Elements Funding
Concept Award (CA) Investigators at or above the level of postdoctoral fellow (or equivalent)
  • Pre-application (Letter of Intent) is required.
  • Supports the exploration of a highly innovative new concept or untested theory that addresses an important problem relevant to reconstructive transplant.
  • Preliminary data are NOT allowed.
  • Reviewers at both tiers of review will be blinded to the identity of the Principal Investigator (PI), collaborators, and their organizations.
  • Applications must address at least one of the FY18 RTRP Focus Areas.
  • Maximum funding of $200,000 for total costs (direct plus indirect costs)
  • Maximum period of performance is 18 months
Investigator-Initiated Research Award (IIRA) Independent investigators at all academic levels (or equivalent)
  • Preproposal is required; full application submission is by invitation only.
  • Supports studies with potential to make an important contribution to the reconstructive transplant research field, patient care, and/or quality of life.
  • Preliminary or published data required.
  • Multiple PI Option supports synergistic partnerships among two to four investigators collaborating on a single application; multi-institutional collaborations are encouraged.
  • Applications must address at least one of the FY18 RTRP Focus Areas.
 Individual PIs:
  • Maximum funding of $1�million (M) for total costs
  • Maximum period of performance is 3 years

Multiple PI Option:

  • Maximum funding of $1.5M for total costs
  • Maximum period of performance is 3 years
Qualitative Research Award (QRA) Independent investigators at all academic levels (or equivalent)
  • Preproposal is required; full application submission is by invitation only.
  • Supports qualitative research studies that will help researchers and clinicians to better understand the experiences of individuals who are considering, or have already, received reconstructive transplant surgery.
  • Demonstrated qualitative research experience within the research team is required.
  • Applications must address the following FY18 RTRP Focus Area:
    • Identify near- and long-term functional, quality-of-life, and psychosocial outcomes in VCA
  • Multiple PI Option supports synergistic partnerships among two to four investigators collaborating on a single application; multi-institutional collaborations are encouraged.
 Individual PIs:
  • Maximum funding of $1M for total costs
  • Maximum period of performance is 3 years
Multiple PI Option:
  • Maximum funding of $1.5M for total costs
  • Maximum period of performance is 3 years.

A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline. All applications must conform to the final Program Announcements and General Application Instructions that will be available for electronic downloading from the Grants.gov website. The application package containing the required forms for each award mechanism will also be found on Grants.gov. A listing of all CDMRP and other USAMRMC extramural funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.

Submission deadlines are not available until the Program Announcements are released. For email notification when Program Announcements are released, subscribe to program-specific news and updates under "Email Subscriptions" on the eBRAP homepage at https://eBRAP.org. For more information about the RTRP or other CDMRP-administered programs, please visit the CDMRP website (httpcdmrp.health.mil.mil).



Point of Contact:

CDMRP Public Affairs
301-619-9783
usarmys.detrick.medcom-cdmrp.mbx.cdmrp-public-affairs@mail.mil


Last updated Monday, December 16, 2024