Peer Reviewed Orthopaedic
Released: January 30, 2017
Defense Health Program
Department of Defense Peer Reviewed Orthopaedic Research Program
Funding Opportunities for Fiscal Year 2017 (FY17)
Due to the current Continuing Resolution, the Fiscal Year 2017 (FY17) Defense Appropriations bill has not been passed. Although funds have not been appropriated for the Department of Defense Peer Reviewed Orthopaedic Research Program (PRORP), the PRORP is providing the information in this pre-announcement to allow investigators time to plan and develop ideas for submission to the anticipated FY17 funding opportunities.
FY17 PRORP Program Announcements and General Application Instructions for the following award mechanisms are anticipated to be posted on Grants.gov in March 2017. Pre-application and application deadlines will be available when the Program Announcements are released. This pre-announcement should not be construed as an obligation by the Government, and funding of research projects received in response to these Program Announcements is contingent on the availability of Federal funds appropriated for the PRORP.
As directed by the Office of the Assistant Secretary of Defense for Health Affairs, the Defense Health Agency (DHA), J9 Research and Development Directorate manages the Defense Health Program (DHP) Research, Development, Test, and Evaluation (RDT&E) appropriation. The managing agent for the anticipated Program Announcements/Funding Opportunities is the Congressionally Directed Medical Research Programs (CDMRP).
Focus Areas: The PRORP will only consider applications that specifically address the critical needs of the orthopaedic research community in one or more of the FY17 Focus Areas. The PRORP will solicit research applications that address at least one of the following FY17 Focus Areas (note that focus area requirements vary by award mechanism):
Surgical Care Focus Areas:
- Peripheral Nerve Injuries: Treatment strategies to improve outcomes from segmental peripheral nerve defects of motor and mixed (motor and sensory) peripheral nerve damage from crush or complete injury.
- Prevention of Heterotopic Ossification: Techniques to retard or prevent the development of human post-traumatic heterotopic ossification in the upper extremity.
- Volumetric Muscle Loss: Techniques to regenerate functional, innervated muscle units in treatment of volumetric muscle loss.
- Extremity Fractures: Strategies to optimize patient outcomes after extremity fracture (i.e., time to begin rehabilitation, weight-bearing strategy, etc.)
- Pelvic Ring Injuries: Treatment strategies to improve outcomes of complex pelvic ring injuries.
- Compartment Syndrome: Strategies to improve current diagnoses for compartment syndrome.
- Gaps in Clinical Practice Guidelines: Address gaps in current orthopaedic clinical practice guidelines (CPG) and recommendations (http://www.usaisr.amedd.army.mil/cpgs.html). Applications under this Focus Area must specify which orthopaedically relevant CPG their application is intended to support. Applicants should also highlight the expected impact of their research on orthopaedic clinical practice.
- Surgical Techniques to Optimize Gait: Validate surgical techniques to optimize gait efficiency and outcomes for patients with amputation or limb salvage.
- Soft Tissue Trauma: Strategies to develop and/or identify musculoskeletal extremity soft tissue trauma treatments optimizing return to duty, work, or reintegration.
- Osteoarthritis: Treatment strategies involving large animal studies, clinical research, or clinical trials to improve outcomes of osteoarthritis and/or post-traumatic osteoarthritis.
Rehabilitation Focus Areas:
- Post-Operative Pain Management: Develop and/or validate strategies for post-operative pain management following orthopaedic trauma that minimize or eliminate opioid use. The primary outcome measures should relate to rehabilitation endpoints and not focus solely on pain scores.
- Prosthetic and/or Orthotic Device Function: Development and optimization of novel, innovative technologies to improve prosthetic and/or orthotic device function and durability, including intuitive efferent (motor) and afferent (sensory) user interfaces and considerations for interoperability.
- Secondary Physical Health Effects: Techniques or technologies that improve prediction, identification, and reduction of secondary physical health effects (e.g., obesity, arthrosis, osteoporosis, cardiovascular disease) following severe/high-energy traumatic neuromusculoskeletal non-spinal cord injury. The focus should be on injuries sustained between the ages of 18-50 and secondary physical health effects that develop within 5 years of injury.
- Physical or Occupational Therapy: Development and/or validation of optimal physical or occupational therapy treatment strategies and sequence of progression throughout the rehabilitation continuum to maximize functional outcomes following severe neuromusculoskeletal injury, excluding central nervous system. Examples include optimal timing, frequency, duration, and intensity of rehabilitation interventions.
- Barriers to Successful Therapy Outcomes: Identify, quantify, and stratify confounding treatable factors (e.g., pain, sleep, nutrition, compliance, etc.) that inhibit or delay optimal orthopaedic rehabilitation outcomes.
- Rehabilitation Outcomes: Development and/or validation of standardized measures to objectively assess and improve rehabilitation outcomes, including multi-extremity trauma and/or psychosocial resiliency and reintegration, following neuromusculoskeletal injury.
- Osteoarthritis: Development and/or validation of optimal physical or occupational therapy treatment strategies to improve outcomes of osteoarthritis and/or post-traumatic osteoarthritis.
|Award Mechanism||Eligibility||Key Mechanism Elements||Funding|
|Applied Research Award||
|Clinical Trial Award||
|Integrated Clinical Trial Award||
|Clinical Translational Research Award||
A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline. All applications must conform to the final Program Announcements and General Application Instructions that will be available for electronic downloading from the Grants.gov website. The application package containing the required forms for each award mechanism will also be found on Grants.gov. A listing of all CDMRP funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.
Applications must be submitted through the federal government’s single-entry portal, Grants.gov. Submission deadlines are not available until the Program Announcements are released. For email notification when Program Announcements are released, subscribe to program-specific news and updates under “Email Subscriptions” on the eBRAP homepage at https://eBRAP.org. For more information about the PRORP or other CDMRP-administered programs, please visit the CDMRP website (https://cdmrp.army.mil).
Point of Contact:
CDMRP Public Affairs