DEPARTMENT OF DEFENSE - CONGRESSIONALLY DIRECTED MEDICAL RESEARCH PROGRAMS
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NEWS RELEASE

Released: January 21, 2010

Department of Defense Peer Reviewed Medical Research Program
Funding for Fiscal Year 2010

The Fiscal Year 2010 (FY10) Defense Appropriations Act provides $50 million to the Department of Defense Peer Reviewed Medical Research Program (PRMRP). The vision of the PRMRP is to identify and fund the best medical research to protect and support warfighters, veterans, and all beneficiaries and to eradicate diseases that impact these populations. The PRMRP challenges the scientific and clinical communities to address one of the FY10 congressionally directed topic areas with original ideas that foster new directions in basic science and translational research; novel product development leading to improved therapeutic or diagnostic tools, or improvements in clinical policies/guidelines; or clinical trials that address an immediate clinical need. This program is administered by the U.S. Army Medical Research and Materiel Command through the Office of the Congressionally Directed Medical Research Programs (CDMRP).

FY10 PRMRP Congressionally Directed Topic Areas: The FY10 PRMRP will solicit research proposals for the following 19 topics areas: chronic migraine and post-traumatic headache; dystonia; drug abuse; epilepsy; fragile X syndrome; inflammatory bowel disease; interstitial cystitis; Listeria vaccine for infectious disease; lupus; mesothelioma; neuroblastoma; osteoporosis and related bone disease; Paget's disease; pheochromocytoma; polycystic kidney disease; post-traumatic osteoarthritis; scleroderma; social work research; and tinnitus.

The FY10 PRMRP award mechanisms are listed in the table below. Mechanism-specific Program Announcements/Funding Opportunities, including submission deadlines, and General Application Instructions are anticipated to be posted on the Grants.gov and CDMRP websites (https://www.grants.gov and https://CDMRP.HEALTH.MIL, respectively) in late January/early February 2010.

Award Mechanism Eligibility Key Mechanism Elements Funding
Concept Award All Investigators
  • To support the exploration of a highly innovative new concept or untested theory
  • Projects involving human subjects or specimens will not be supported unless they are exempt under Title 32, Code of Federal Regulations, Part 219, Section 101(b)(32 CFR 219.101[b])
  • Maximum of $75,000 for direct costs (plus indirect costs)
  • Maximum period of performance is 1 year
  • Anticipate 33 awards
Investigator-Initiated Research Award Assistant Professor level or above (or equivalent)
  • To support military-relevant health-related research that will make an original and important contribution to the field of research or patient care in the topic area of interest
  • Clinical trials will not be funded
  • Partnering Principal Investigator option available
  • Preproposal is required; proposal submission is by invitation only
  • Preproposal submission is required; application submission is by invitation only
  • Maximum of $725,000 for direct costs (plus indirect costs)
  • Maximum period of performance is 3 years
  • Anticipate 26 awards
Technology/Therapeutic Development Award Assistant Professor level or above (or equivalent)
  • To support military-relevant health-related development of new diagnostics, therapies, or clinical policy/guidance that has the potential to make a strong impact on patient care in the topic area of interest
  • Product-oriented
    • Device
    • Drug
    • Clinical policy/guidance
  • Clinical trials will not be funded
  • Maximum of $1.7 million for direct costs (plus indirect costs)
  • Maximum period of performance is 4 years
  • Anticipate 2 awards
Clinical Trial Award Assistant Professor level or above (or equivalent)
  • To support rapid implementation of military-relevant health-related clinical trials of novel interventions with the potential to have a significant impact
  • IND (Investigational New Drug) or IDE (Investigational Device Exemption) applications should be submitted/completed before proposal submission
  • Clinical trial is expected to be initiated within 12 months of award date
  • Maximum of $2.2 million for direct costs (plus indirect costs)
  • Maximum period of performance is 5 years
  • Anticipate 2 awards

Information in this press release regarding the Concept Award, Investigator-Initiated Research Award, Technology/Therapeutic Development Award, and Clinical Trial Award mechanisms is being provided to allow investigators time to plan and develop applications. All applications submitted must conform to the requirements specified in the relevant Program Announcement/Funding Opportunity, which will be posted on Grants.gov at a later date. Pre-application and application deadlines will not be available until these Program Announcements are released.

The number of awards anticipated is based on available funds and the average cost of applications. The PRMRP reserves the right to make awards in greater or lesser numbers than anticipated based on the number and quality of applications received. Each Program Announcement/Funding Opportunity and the General Application Instructions, which detail the pre-application and application submission requirements and process, along with the required forms for application submission, will be available for downloading from the Grants.gov website (https://www.grants.gov) upon release.

Pre-application submission to the CDMRP eReceipt website (https://cdmrp.org) prior to application submission is required for all award mechanisms. Applications must be submitted through the federal government's single-entry portal, Grants.gov (https://www.grants.gov). A listing of all USAMRMC funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420. Pre-application and application submission deadlines will be listed in each Program Announcement/Funding Opportunity.

Requests for email notification of the Program Announcement release may be sent to Help@cdmrp.org. For more information about the PRMRP or other CDMRP-sponsored programs, please visit the CDMRP website (https://CDMRP.HEALTH.MIL).

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