IMPORTANT: All applications for FY10 PCRP funding must address at least one of the FY10 PCRP Overarching
Challenges and at least one of the six PCRP Focus Areas:
- Overarching Challenges: Development of effective treatments for advanced disease, Distinguishing lethal
from indolent disease
- Focus Areas: Imaging, Biomarkers, Therapy, Genetics, Tumor Biology, Survivorship
|
| Award Mechanism |
Eligibility |
Key Mechanism Elements |
Funding |
| Exploration-Hypothesis Development Award |
Investigators at all academic levels (or equivalent) |
- Supports highly innovative, untested, potentially groundbreaking concepts in prostate cancer
- Emphasis is on Innovation; potential impact may be unknown
- Human studies investigation is permitted provided it is exempt
- Preliminary data are not allowed
|
- Maximum funding of $75K for direct costs (plus indirect costs)
- Period of performance cannot exceed 18 months
|
| Health Disparity Research Award |
Independent investigators at or above the level of Assistant Professor (or equivalent); OR
NEW for FY10!
New Investigator Option: PIs must meet the following criteria at the application submission deadline:
- Must be an independent investigator (have the freedom to pursue individual aims without formal mentorship), AND
- Have not previously received a PCRP New Investigator Award, AND
- Either have completed at least 3 years of postdoctoral training or fellowship OR are within 5 years of having received
first independent faculty position (or equivalent)
|
- Supports new ideas that represent innovative, high-risk/high-gain approaches to prostate cancer health
disparity research that have the potential to make an important contribution to eliminating death and
suffering from prostate cancer
- PI(s) and/or collaborator(s) should have a connection to, or effectiveness in working with, an affected population or community
- Preliminary data are encouraged but not required
- Emphasis is on Innovation and Impact
- Clinical trials are not allowed
|
- Maximum funding of $450K for direct costs (plus indirect costs)
- Period of performance cannot exceed 3 years
|
| Health Disparity Training Award |
Predoctoral Ph.D. and M.D./Ph.D. PIs:
- Must be enrolled full-time in an accredited doctoral program and must have completed all predissertation
requirements by October 1, 2010
Postdoctoral Ph.D. PIs:
- Must have successfully defended a doctoral thesis by October 1, 2010; and
- Have 3 years or less of postdoctoral fellowship experience by October 1, 2010
Postdoctoral M.D. PIs:
- Must have an M.D.; AND
- Must be able to devote at least 40% effort; AND
- By August 1, 2010, must be:
- Enrolled in an accredited intern training program, OR
- Enrolled in an accredited residency or fellowship program with at least 2 years of training remaining,
OR
- Within 3 years of the last formal training
|
- Supports training in prostate cancer health disparity research for individuals in the early stages of their careers
- PIs must have a designated mentor who is an experienced prostate cancer health disparity researcher
- PI or mentor must demonstrate a connection to, or effectiveness in working with, the affected population or community
- Emphasis is on PI, Mentor, and Training Program and Environment
|
Predoctoral Ph.D. and M.D./Ph.D. PIs:
- Maximum funding of $92.5K for direct costs (plus 8% indirect costs)
- Period of performance cannot exceed 3 years
Postdoctoral M.D. or Ph.D. PIs:
- Maximum of $115K for direct costs (plus 8% indirect costs)
- Period of performance cannot exceed 2 years
|
| Idea Development Award |
NEW for FY10!
New Investigator Option: Principal Investigators (PIs) must meet the following criteria at the application
submission deadline:
- Must be an independent investigator (have the freedom to pursue individual aims without formal
mentorship), AND
- Have not previously received a PCRP New Investigator Award, AND
- Either have completed at least 3 years of postdoctoral training or fellowship OR are within 5 years of
having received first independent faculty position (or equivalent)
|
- Preproposal is required; application submission is by invitation only
- Supports new ideas that represent innovative, high-risk/high-gain approaches to prostate cancer research,
and have the potential to make an important contribution to eliminating death and suffering from prostate
cancer
- Preliminary data are encouraged but not required
- Emphasis is on Innovation and Impact
- Clinical trials are not allowed
- New Investigator Option supports applicants early in their faculty appointments or in the process of
developing independent research careers
|
- Maximum funding of $450K for direct costs (plus indirect costs)
- Period of performance cannot exceed 3 years
|
| Impact Award (NEW!) |
Independent investigators at or above the level of Assistant Professor (or equivalent) |
- Preproposal is required; application submission is by invitation only
- Supports high-impact studies towards reducing or eliminating the problem of overtreatment of primary
prostate cancer
- Areas of special interest include but are not limited to active surveillance, biomarkers, improved
staging, local staging, and optimal measures for follow-up and biopsy
- Multidisciplinary teams inclusive of strong clinical expertise are a key feature
- Preliminary data to support feasibility are required
- Emphasis is on the Research Question and Impact
- Allows clinical trials
|
- Maximum funding of $750K for direct cost (plus indirect costs)
- Period of performance cannot exceed 3 years
|
| Laboratory- Clinical Transition Award |
Investigators at all academic levels (or equivalent) |
- Supports goal- and product-driven preclinical studies of promising lead agents or targets that may
revolutionize prostate cancer clinical care
- PIs are expected to have identified and have access to either one lead agent or a limited number of lead
agents for optimization, or a validated target before applying
- Preliminary data are required to demonstrate validated target availability or lead agent(s) in human
prostate cancer
- Does not support target discovery, drug screening, device development, development of diagnostic
biomarkers, studies of conventional therapeutics, or clinical trials
- Emphasis is on Lead Agent, Research Strategy, and Clinical Impact
|
- Maximum funding of $750K for direct costs (plus indirect costs)
- Period of performance cannot exceed 3 years
|
| Physician Research Training Award |
At the time of proposal submission, the PI must be either:
- A physician with clinical duties and/or responsibilities in the last year of an accredited medical
residency or medical fellowship program; or
- A physician within 3 years of first independent faculty appointment
|
- Supports training of physicians with clinical duties for careers in prostate cancer research
- PIs must have a designated mentor with an established research program in prostate cancer
- Institutions must provide at least 40% protection of PI's time for research
- Emphasis is on PI, Mentor, and Training Program and Environment
|
- Maximum funding of $130K per year for direct costs (plus 8% indirect costs)
- Period of performance is 3 years minimum to 5 years maximum
|
| Population-Based Research Award |
Independent investigators at or above the level of Assistant Professor (or equivalent) |
- Supports high-impact approaches to prostate cancer research from the perspective of population-based
studies that will, if successful, significantly accelerate the elimination of death and suffering from
prostate cancer
- Population-based studies may include case-control, retrospective, prospective, and cohort studies
provided that the study population is of sufficient size to provide appropriate statistical power
- Topics may include but are not limited to epidemiology, molecular genetics, germline and somatic
genomics, risk prediction, disease aggressiveness, predictors of therapeutic response and progression, and
health disparity
- Requires a robust statistical plan and strong biostatistical expertise in the study team
- Emphasis is on Impact and Research Strategy and Feasibility
- Clinical trials are not allowed
|
- Maximum funding of $600K for direct costs (plus indirect costs)
- Period of performance cannot exceed 4 years
|
| Prostate Cancer Training Award |
Postdoctoral Ph.D. PIs:
- Must be enrolled full-time in an accredited doctoral program and must have completed all predissertation
requirements by October 1, 2010
Must have successfully defended a doctoral thesis by October 1, 2010; and
- Must have successfully defended a doctoral thesis by October 1, 2010; and
- Have 3 years or less of postdoctoral fellowship experience by October 1, 2010
Postdoctoral M.D. PIs:
- Must have an M.D.; AND
- Must be able to devote at least 40% effort; AND
- By August 1, 2010, must be:
- Enrolled in an accredited intern training program, OR
- Enrolled in an accredited residency or fellowship program with at least 2 years of training
remaining, OR
- Within 3 years of the last formal training
|
- Supports prostate cancer research training for individuals in the early stages of their careers
- PIs must have a designated mentor
- Emphasis is on PI, Mentor, and Training Program and Environment
|
- Predoctoral Ph.D. and M.D./Ph.D. PIs:
- Maximum funding of $92.5K for direct costs (plus 8% indirect costs)
- Period of performance cannot exceed 3 years
- Postdoctoral M.D. or Ph.D. PIs:
- Maximum of $115K for direct costs (plus 8% indirect costs)
- Period of performance cannot exceed 2 years
|
| Synergistic Idea Development Award |
Two or three independent investigators at or above the level of Assistant Professor (or equivalent) |
- Preproposal is required; application submission is by invitation only
- Supports new or existing partnerships between two or three independent investigators to address a
central innovative question in prostate cancer that may include high risk, provided there is a potential for
significant impact
- Preliminary data are encouraged but not required
- Emphasis is on Synergy, Innovation, and Impact
- Clinical trials are not allowed
|
- Maximum funding of $750K for direct costs (plus indirect costs)
- Period of performance cannot exceed 3 years
|
