DEPARTMENT OF DEFENSE - CONGRESSIONALLY DIRECTED MEDICAL RESEARCH PROGRAMS

NEWS RELEASE

Released: December 22, 2008

Department of Defense Peer Reviewed Medical Research Program
Funding Opportunities for Fiscal Year 2009

The Fiscal Year 2009 (FY09) Defense Appropriations Act provides $50 million to the Department of Defense Peer Reviewed Medical Research Program (PRMRP) to provide support for exceptional medical research to protect and support military personnel and all beneficiaries and to eradicate diseases that impact these populations. This program is administered by the US Army Medical Research and Materiel Command through the Office of the Congressionally Directed Medical Research Programs (CDMRP).

FY09 PRMRP Congressionally Directed Topic Areas:
Proposed research must be focused in one of the following 19 topic areas: Alcoholism Research; Autoimmune Diseases; Blood Cancer; Childhood Asthma; Drug Abuse; Epilepsy; Kidney Cancer; Listeria Vaccine for Infectious Diseases and Cancer; Lupus, Mesothelioma; Molecular Signatures in Tumors; Neuroblastoma; Osteoporosis and Related Bone Disease; Paget's Disease; Pediatric Cancer; Polycystic Kidney Disease; Social Work Research; Tinnitus; West Nile Virus Vaccine.

FY09 PRMRP Program Announcements will be released in January 2009 for the award mechanisms listed in the table below.

Award Mechanism Eligibility Key Mechanism Elements Funding
Investigator-Initiated Research Award

*New description for FY09*
Assistant Professor level or above (or equivalent)
  • To support military-relevant health-related research that will make an original and important contribution to the field of research or patient care in the topic area of interest
  • Translational potential of the proposed research must be addressed
  • Clinical trials will not be funded
  • Partnering PI option available
  • A maximum of $750,000 for direct costs for up to a 3-year performance period, plus indirect costs as appropriate
  • Anticipate 28 awards
Technology/Therapeutic Development Award Assistant Professor level or above (or equivalent)
  • To support military-relevant health-related development of new diagnostics, therapies, or clinical policy/guidance that has the potential to make a strong impact on patient care in the topic area of interest
  • Product-oriented
    • Device
    • Drug
    • Clinical policy/guidance
  • Clinical trials will not be funded
  • A maximum of $2.0 million for direct costs for up to a 4-year performance period, plus indirect costs as appropriate
  • Anticipate 2 awards
Clinical Trial Award Assistant Professor level or above (or equivalent)
  • To support rapid implementation of military-relevant health-related clinical trials of novel interventions with the potential to have a significant impact
  • IND* or IDE↑ applications should be submitted/completed before proposal submission
  • Clinical trial is expected to be initiated within12 months of award date
  • A maximum of $2.5 million for direct costs for up to a 5-year performance period, plus indirect costs as appropriate
  • Anticipate 2 awards

* Investigational New Drug
↑ Investigational Device Exemption

Information in this preannouncement is being provided to allow investigators time to plan and develop proposals. All applications submitted must conform to the requirements specified in the final Program Announcements, to be posted in Grants.gov by the end of January 2009. The number of awards anticipated is based on available funds and average cost of proposals. The PRMRP reserves the right to make awards in greater or lesser numbers than anticipated. As of 2007, proposals requesting funding from the CDMRP have been submitted through the Federal Government's single-entry portal, Grants.gov, in compliance with Public Law 106-107. Each Program Announcement and corresponding Application Instructions & General Information, detailing the pre-application and application submission process, along with the required forms for proposal submission, will be available electronically for downloading from the Grants.gov website (https://www.grants.gov) upon release. Also, Program Announcements and corresponding Application Instructions & General Information will be available on the CDMRP website (https://CDMRP.HEALTH.MIL). Each award mechanism will require submission of a pre-application including a letter of intent (LOI) through the CDMRP eReceipt website, https://cdmrp.org. Pre-application LOI and application submission deadlines will be listed in the Program Announcements.

Requests for email notification of the FY09 PRMRP Program Announcement release may be sent to Help@cdmrp.org. For more information about the PRMRP or other CDMRP-sponsored programs, please visit the CDMRP website.

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