Idea Development Award

Must be an independent investigator

• Fund high impact, innovative research that will drive the field forward
• Proposals in all areas of research are accepted
• Proposals in the following three areas are encouraged:
• Identification and characterization of early changes associated with ovarian cancer
• Identification and characterization of ovarian cancer stem cells
• Contribution of the stroma to the tumor microenvironment in ovarian cancer
• Preliminary data relevant to the proposed project, but not necessarily in ovarian cancer, are required
• Preproposal is required; proposal submission is by invitation only

NEW FOR FY08:

• Non-Traditional Collaboration (optional): Collaborations that meet the criteria outlined in the program announcement will be qualified for a higher level of funding. Non-traditional collaboration is between an academic institution and a biotechnology/ pharmaceutical company; or between an academic institution and a foundation; or between a biotechnology/pharmaceutical company and a foundation
• Clinical trials are allowed

• A maximum of $375,000 for direct costs for up to a 3-year performance period, plus indirect costs as appropriate
• Proposals with a qualified non-traditional collaboration can request a maximum of $450,000 for direct costs for up to a 3-year performance period, plus indirect costs as appropriate
• Anticipate 4-5 awards

Translational Research Partnership Award

• Initiating Principal Investigator (PI): Must be an independent investigator
• Partnering PI: Must be an independent investigator

• Fund partnerships between clinicians and laboratory scientists that accelerate the movement of promising ideas in ovarian cancer into clinical applications
• Partnership:
• One partner must be a laboratory scientist, and the other must be a clinician
• Each partner will be a PI
• Proposals in all areas of research are accepted
• Proposals in the following three areas are encouraged:
• Identification and characterization of early changes associated with ovarian cancer
• Identification and characterization of ovarian cancer stem cells
• Contribution of the stroma to the tumor microenvironment in ovarian cancer
• Clinical trials are not allowed
• Preliminary data relevant to the proposed project, but not necessarily in ovarian cancer, are required
• Preproposal is required; proposal submission is by invitation only

NEW FOR FY08:

• Non-Traditional Partnership (optional): Partnerships that meet the criteria outlined in the program announcement will be qualified for a higher level of funding. Non-traditional partnership is between an academic institution and a biotechnology/ pharmaceutical company; or between an academic institution and a foundation; or between a biotechnology/pharmaceutical company and a foundation

• A separate award will be made to each partner's institution. The maximum combined funding for both awards is $750,000 for direct costs for up to a 3-year performance period, plus indirect costs as appropriate
• Proposals with a qualified non-traditional partnership can request a maximum combined funding of $825,000 for direct costs for up to a 3-year performance period, plus indirect costs as appropriate
• Anticipate 2 awards

Career Development Award

At the time of proposal submission:

• Postdoctoral Fellow: Must be within 5 years of doctoral degree; or
• Early-Career Investigator: Must be within 3 years of having completed postdoctoral or fellowship training, and have received less than $300,000 in direct costs in aggregate for ovarian cancer research as PI of federally or privately funded, non-mentored, peer reviewed grants

• Provide research training opportunities focused on ovarian cancer research to individuals in the early stages of their career
• Designated Mentor who is an experienced ovarian cancer researcher for Postdoctoral Fellow is required
• Designated Collaborator who is an experienced ovarian cancer researcher for Early-Career Investigator is required
• Proposals in all areas of research are accepted
• Proposals in the following three areas are encouraged:
• Identification and characterization of early changes associated with ovarian cancer
• Identification and characterization of ovarian cancer stem cells
• The contribution of the stroma to the tumor microenvironment in ovarian cancer
• Preliminary data relevant to the proposed project, but not necessarily in ovarian cancer, are required
• Clinical trials are not allowed

• For Postdoctoral Fellow: A maximum of $300,000 for direct costs for up to a 3-year performance period, plus indirect costs as appropriate
• For Early-Career Investigator: A maximum of $375,000 for direct costs for up to a 3-year performance period, plus indirect costs as appropriate
• Anticipate 6 awards in total

Consortium Development Award

Must be an independent investigator at or above the level of Assistant Professor (or equivalent)

• Support for establishing the necessary collaborations and developing a plan and budget for a consortium which will focus only on the issue of identification and characterization of early changes associated with ovarian cancer
• Funds may not be used to support research
• Funded applicants will be eligible to compete for a consortium award to be offered in FY09

• A maximum of $150,000 for direct costs for up to a 1-year performance period, plus indirect costs as appropriate
• Anticipate 2 awards