DEPARTMENT OF DEFENSE - CONGRESSIONALLY DIRECTED MEDICAL RESEARCH PROGRAMS

NEWS RELEASE

Released: December 19, 2007

Department of Defense Breast Cancer Research Program
Funding Opportunities for Fiscal Year 2008

The Fiscal Year 2008 (FY08) Defense Appropriations Act provides $138 million (M) to the Department of Defense Breast Cancer Research Program (BCRP) to support innovative research aimed at eradicating breast cancer. This program is administered by the US Army Medical Research and Materiel Command through the Office of the Congressionally Directed Medical Research Programs (CDMRP).

FY08 BCRP program announcements for the following mechanisms are anticipated to be released in February 2008, unless noted otherwise:

Award Mechanism

Eligibility

Key Mechanism Elements

Funding

Clinical Translational Research Award

Investigators at all academic levels (or equivalent)

  • Supports the acceleration of innovative preclinical research with a high potential for direct clinical translation that will result in substantial improvements over current approaches to breast cancer chemoprevention and/or therapy
  • Must have a clinical trial with at least 1 year of patient accrual within the lifetime of the award
  • Preliminary data is required
  • Preproposal is required; proposal submission is by invitation only

  • No maximum dollar limit for up to 5 years
  • No more than $5M will be granted within any single year during the lifetime of the award

Era of Hope Postdoctoral Award

Doctoral graduates (PhD or MD)

No more than 2 years in the proposed research setting and no more than 4 years postdoctoral research experience

  • Supports exceptionally talented recent doctoral graduates who have the ambition and ability to pursue highly innovative breast cancer work during their postdoctoral training
  • Proposed research should be innovative and challenge current scientific dogma
  • Nomination letter is required; proposal submission is by invitation only

  • $270K for direct costs for up to 3 years, plus indirect costs as appropriate
  • Era of Hope Scholar Award

    Independent, non-mentored investigators within 6 years of their last mentored position as of the nomination deadline

    • Supports exceptionally talented, creative early-career scientists who have demonstrated that they are the "best and brightest" in their fields
    • Individuals should exhibit strong potential for leadership in the breast cancer community
    • Nomination letter is required; proposal submission is by invitation only

  • $2.5M for direct costs for up to 5 years, plus indirect costs as appropriate
  • HBCU/MI Partnership Training Award

    Principal Investigator/Co-investigator(s): HBCU/MI faculty member with doctoral degree

    Mentor(s): Must have an established breast cancer research program at the mentoring institution

    • Supports two or more faculty-level investigators at an HBCU/MI to acquire mentored training in breast cancer research
    • Supports the establishment of a sustainable breast cancer research program at the applicant HBCU/MI
    • Proposed research and training should lead to publication(s) and independent breast cancer research funding

  • $1M for direct costs for up to 4 years, plus indirect costs as appropriate
  • Idea Award

    Investigators at all academic levels (or equivalent)

    • Supports highly innovative, high-risk/high-reward research from all areas of basic, translational, clinical, behavioral, and epidemiological research
    • Innovation is the most important review criterion
    • No preliminary data required, but proposal should include a sound scientific rationale

    • $375K for direct costs for up to 3 years, plus indirect costs as appropriate
    • For population-based studies: $650K for direct costs for up to 5 years, plus indirect costs as appropriate

    Impact Award

    Investigators at all academic levels (or equivalent)

    • Supports unique projects or ideas (from small- to large-scale) that possess strong potential to have an unprecedented impact in breast cancer
    • Impact is the most important review criterion (innovation is not a criterion)
    • Impact may be scientific or clinical and may be short- or long-term

  • A maximum of $5M for direct costs for up to 5 years, plus indirect costs as appropriate
  • Innovator Award

    Investigators at all academic levels (or equivalent)

    • Supports visionary individuals with a history of creativity, innovative work, and leadership in any field
    • Provides opportunity to pursue novel, visionary, high-risk ideas that could ultimately lead to the eradication of breast cancer
    • Nomination letter is required; proposal submission is by invitation only

  • $5M for direct costs for up to 5 years, plus indirect costs as appropriate
  • Predoctoral Traineeship Award (release date: December 18, 2007)

    Principal Investigator: Graduate student (PhD or MD/PhD)

    Mentor: Must have breast cancer experience, to include current funding and recent publications

    • Supports the preparation of promising graduate students studying breast cancer research under the guidance of a designated mentor
    • The predoctoral trainee is considered the PI and should write the proposal with appropriate direction from the mentor
    • Training program should prepare the trainee for an independent career in breast cancer research

  • $90K for direct costs for up to 3 years, plus indirect costs as appropriate
  • Synergistic Idea Award

    Two independent, faculty-level (or equivalent) investigators

    • Supports two investigators who address an innovative, high-risk, potentially high-reward breast cancer question from synergistic and complementary perspectives
    • Innovation and synergy are the most important review criteria
    • No preliminary data required, but proposal should include a sound scientific rationale

    • $500K for direct costs for up to 2 years, plus indirect costs as appropriate
    • For population-based studies: $850K for direct costs for up to 5 years, plus indirect costs as appropriate

    Information in this preannouncement is being provided to allow investigators time to plan and develop proposals. All proposals submitted must conform to the final program announcements, to be posted in Grants.gov in early 2008. Each program announcement will be available electronically for downloading from the Grants.gov website.

    A pre-application is required and must be submitted through the CDMRP e-Receipt website, https://cdmrp.org. As of 2007, all proposals requesting funding from the CDMRP must be submitted through the Federal Government's single entry portal, Grants.gov, in compliance with Public Law 106-107. Individual program announcements and required forms will also be found on that website.

    Requests for email notification of the program announcement release may be sent to Help@cdmrp.org. For more information about the BCRP or other CDMRP-sponsored programs, please visit the CDMRP website.

    Point of Contact: