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Complementary & Alternative Medicine


Effectiveness of Acupuncture in the Treatment of Gulf War Illness

Summary: This was clinical trial of acupuncture to address symptoms of Gulf War illness. With 104 veterans enrolled, the study found significant improvement in self-reported health outcomes and pain scores for those in the bi-weekly treatment group. Participants also responded favorably to their experience with acupuncture and acupuncturists. Identifier: NCT01305811

Status (2021): COMPLETED


Gulf War Illness: Evaluation of an Innovative Detoxification Program

Summary: A total of 31 ill Gulf War veterans completed the detoxification program. Participants reported improved health upon completion of the program. Identifier: NCT01672710

Status (2021): COMPLETED


Nasal Irrigation for Chronic Rhinosinusitis and Fatigue in Patients with Gulf War Syndrome

Summary: Enrollment did not achieve the initial estimate of 60 participants, but the results suggested that nasal irrigation can provide effective adjunct therapy for chronic rhinosinusitis and fatigue in adults with GWI. Identifier: NCT01700725

Status (2021): COMPLETED


Investigating Clinical Benefits of a Novel Sleep-Focused, Mind-Body Program on Gulf War Illness Symptoms: An Exploratory Randomized Controlled Trial

Summary: In 60 subjects, Mind-Body Bridging (MBB) was efficacious in reducing disturbed sleep in comparison with control. Sleep-focused MBB also was efficacious in decreasing self-reported outcomes of PTSD, depression, and mental fatigue. Identifier: NCT01543997

Status (2021): COMPLETED


A Multimodal Evaluation of the Comparative Efficacy of Yoga versus a Patient-Centered Support Group for Treating Chronic Pain in Gulf War Illness

Summary: All data has been collected from 75 Gulf War veterans who participated and publication of the results is pending. The yoga intervention group showed significant improvement in the primary pain scale outcome. Identifier: NCT02378025

Status (2021): COMPLETED


Use of a Portable Stimulator to Treat GWI

Summary: The study found over half (34 of 64) of Gulf War veteran participants demonstrated vestibular hypofunction. Low levels of random electrical noise were shown to improve both vestibular function and balance in veterans. Identifier: N/A

Status (2021): COMPLETED


Intranasal Insulin: A Novel Treatment for Gulf War Multisymptom Illness

Summary: This pilot clinical trial aimed to test the ability of intranasal insulin to improve memory, attention and mood, and reduce neuroinflammation in symptomatic Gulf War veterans. Study activity is completed, analyses are underway. Identifier: NCT01802944

Status (2021): COMPLETED


Effect of Diet on Gulf War Illness: A Pilot Study

Summary: FODMAPs are Fermentable Oligo-, Di and Mono-saccharides and Polyols, which are carbohydrates that are poorly absorbed in the small intestine. This study will demonstrate the safety and effectiveness of a low FODMAP diet to improve symptoms related to Gulf War illness. Identifier: NCT02881944

Status (2021): Enrollment closed, in data analysis


Glutamate Neuroexcitotoxicity in GWI

Summary: Based on positive findings in a fibromyalgia cohort, this study aims to test the utility of a reduced glutamate diet to reduce symptoms of fatigue, headache, muscle pain and concentration in ill Gulf War veterans. Identifier: NCT03342482

Status (2021): COMPLETED


Pilot Test of Apnea and Insomnia Relief for Veterans with Gulf War Illness

Summary: This pilot study aims to treat obstructive sleep apnea and insomnia in tandem to reduce GWI symptoms in Veterans with GWI and obstructive sleep apnea and insomnia, utilizing an innovative behavioral intervention. Identifier: PENDING

Status (2021): PENDING

Last updated Thursday, May 26, 2022