Summary: This was clinical trial of acupuncture to address symptoms of Gulf War illness. With 104 veterans enrolled, the study found significant improvement in self-reported health outcomes and pain scores for those in the bi-weekly treatment group. Participants also responded favorably to their experience with acupuncture and acupuncturists.

ClinicalTrials.gov Identifier: NCT01305811

Status (2021): COMPLETED

Summary: A total of 31 ill Gulf War veterans completed the detoxification program. Participants reported improved health upon completion of the program.

ClinicalTrials.gov Identifier: NCT01672710

Status (2021): COMPLETED

Summary: Enrollment did not achieve the initial estimate of 60 participants, but the results suggested that nasal irrigation can provide effective adjunct therapy for chronic rhinosinusitis and fatigue in adults with GWI.

ClinicalTrials.gov Identifier: NCT01700725

Status (2021): COMPLETED

Summary: In 60 subjects, Mind-Body Bridging (MBB) was efficacious in reducing disturbed sleep in comparison with control. Sleep-focused MBB also was efficacious in decreasing self-reported outcomes of PTSD, depression, and mental fatigue.

ClinicalTrials.gov Identifier: NCT01543997

Status (2021): COMPLETED

Summary: All data has been collected from 75 Gulf War veterans who participated and publication of the results is pending. The yoga intervention group showed significant improvement in the primary pain scale outcome.

ClinicalTrials.gov Identifier: NCT02378025

Status (2021): COMPLETED

Summary: The study found over half (34 of 64) of Gulf War veteran participants demonstrated vestibular hypofunction. Low levels of random electrical noise were shown to improve both vestibular function and balance in veterans.

ClinicalTrials.gov Identifier: N/A

Status (2021): COMPLETED

Summary: This pilot clinical trial aimed to test the ability of intranasal insulin to improve memory, attention and mood, and reduce neuroinflammation in symptomatic Gulf War veterans. Study activity is completed, analyses are underway.

ClinicalTrials.gov Identifier: NCT01802944

Status (2021): COMPLETED

Summary: FODMAPs are Fermentable Oligo-, Di and Mono-saccharides and Polyols, which are carbohydrates that are poorly absorbed in the small intestine. This study will demonstrate the safety and effectiveness of a low FODMAP diet to improve symptoms related to Gulf War illness.

ClinicalTrials.gov Identifier: NCT02881944

Status (2021): Enrollment closed, in data analysis

Summary: Based on positive findings in a fibromyalgia cohort, this study aims to test the utility of a reduced glutamate diet to reduce symptoms of fatigue, headache, muscle pain and concentration in ill Gulf War veterans.

ClinicalTrials.gov Identifier: NCT03342482

Status (2021): COMPLETED

Summary: This pilot study aims to treat obstructive sleep apnea and insomnia in tandem to reduce GWI symptoms in Veterans with GWI and obstructive sleep apnea and insomnia, utilizing an innovative behavioral intervention.

ClinicalTrials.gov Identifier: PENDING

Status (2021): PENDING